Instituto de Investigación Biomédica de Salamanca
The integrated proposal coordinated by the National DNA Bank within the Biomedical Research Institute of Salamanca (IBSAL, https://ibsal.es/es/) is made up of three complementary units with a history of joint collaboration, as support research services, of more than 15 years (https://www.bancoadn.org/en/structure). The National DNA Bank is a reference biobank not only for its high quality facilities and technical capacities, but also for the unique and singular sample collections that offers to the scientific community (www.bancoadn.org). The Biobank Network of Oncological Diseases of Castilla and León which is made up of seven hospital based biobank spread out the region, also offers as a Comparative Pathology Service (https://www.cicancer.org/core-facilities-services/diagnostic-units/molecular-pathology) complete histological, immunohistochemical and molecular analysis of transgenic animal models, that can be generated on demand within the Transgenesis Service (https://nucleus.usal.es/es/transgenesis) of this Research Support Platform.
Services
RELEVANT SERVICES OFFERED:
1. SAMPLE COLLECTIONS (DNAg, RNA, plasma, cells…)
• HEALTHY representative samples (CONTROL) of the SPANISH POPULATION.
• PREVALENT DISEASES: 1) Chronic inflammatory/autoimmune diseases; 2) Oncological; 3) Metabolic; 4) Cardiovascular; 5) Neuropsychiatric; 6) Fibromyalgia and Chronic Fatigue Syndrome; and 7) COVID-19.
• RARE DISEASES: 1) Mastocytosis; 2) Neurofibromatosis; 3) Primary Immune Thrombocytopenia; 4) Paroxysmal Nocturnal Hemoglobinuria; 5) Amyotrophic Lateral Sclerosis; 6) Autoimmune endocrinopathies; and 7) Idiopathic Cervical Dystonia.
2. SERVICES:
• Preparation of nucleic acid samples (DNA and RNA) and quality control.
• Immortalization of lymphoblastoid cell lines.
• Preparation of biological samples for storage at room temperature.
• Comparative Pathology Service: histological, immunohistochemical and molecular analyses; diagnostic pathology of transgenic mouse models; laser microdissection; tissue microarray (TMA) production and analysis; DOT SLIDE Virtual Microscope for Scanning Samples
• On-demand production of transgenic mouse models with diseases.
