Advanced 3D Printing Services and Biobank Unit Focused on the Health Sector
The SAIBSAL-FIHGUV Unit is composed of a team from the Foundation for Research of the General Hospital of Valencia (FIHGUV), which includes the Biomedical and Tissue Engineering Laboratory (BTELab), the Hospital’s Biobank, members of the Consortium, and two international partners from Harvard University and the pharmaceutical company AstraZeneca. The Unit is located within the FIHGUV, a public entity established in 1999 with the mission of promoting health and translational biomedical research. The FIHGUV supports research projects that optimize medical and surgical processes, and it includes a Clinical Research Unit, a Scientific Unit for Business Innovation, and a Clinical Simulation Center. SAIBSAL-FIHGUV is part of the 3D Printing and Biobank Hubs, which simplifies the application processes and improves user services.
Services
3D Printing:
– High-precision 3D printing of anatomical models for surgical planning and teaching. The service includes DICOM file processing, 3D printing, model sterilization, and distribution in compliance with ISO 13485 standards.
– 3D digitization of Tissue Bank for clinical use through advanced 3D scanning techniques.
– Design, manufacture, and enhancement of technology used in 3D printing and bioprinting.
– Development of 3D digital anatomical biomodels for virtual and augmented reality
– Training and education in robotic surgery through the Cátedra de Robótica of the FIHGUV.
Biofabrication and Microfluidics:
– Development and validation of highly efficient visible light photopolymerizable bioinks.
– Biofabrication of 3D culture systems from stem cells and other cell types, including 3D bioprinting with DLP and extrusion, spheroids, and organoids.
– Design, microfabrication, and cultivation of microfluidic organ-on-chip platforms for disease modeling and drug testing applications.
Cell Culture in Clean Rooms:
– Isolation, cultivation, and characterization of various cells and tissues, including validated animal-derived reagent-free protocols for stem cells.
– Cytotoxicity testing of drugs, cosmetics, and medical devices according to ISO 10993-5 standards (currently undergoing accreditation).
– Molecular biology for the characterization of gene expression and markers.
– Ultrastructural characterization using transmission and scanning electron microscopy.
Biobank
-Transfer of biological material
-Processing and aliquoting of biological samples
– Cryopreservation of cells/tissues
– Nucleic acid extraction
– PBMC isolation.
– Storage of sample collections at -80ºC and in liquid nitrogen.
– Ethical and legal advice
– Bioanalysis of samples: biochemistry, hematometry, hemostasis, hormones, immunology, biological fluids.
– Histology services: OCT and kerosene embedding, histological sections, H&E and IHQ staining, mutation study by RT-PCR, FISH techniques.
